Dramatic performance enhancement of evanescent-wave multimode fiber fluorometer using non-Lambertian light diffuser
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Updated: Jun 22, 2026

Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers
Published on: May 5, 2016
Abstract:
To enhance the performance of an evanescent-wave (EW) based sensor, efforts are usually made to modify the sensor architecture rather than the excitation source. In this paper, we theoretically examine the role of meridian and skew rays under total internal reflection (TIR) as well as tunneling rays with the emphasis on sensor performance. Our further investigation indicates that the intensity profile of the light source enormously influences the EW power, and thus the collectable fluorescent emission level as well. A non-Lambertian fiber-optic side-emitting diffuser (FOSED) is proposed and experimentally verified, revealing that a proper alignment of this FOSED can dramatically improve the signal quality and reduce the level of stray excitation light. In particular, the adoption of a FOSED or other light diffusers with similar output profiles will ensure that the excitation power is used more efficiently, suggesting a lower demand on the excitation source power level, and the performance of the stray light filter and detector. The superiority of this innovation is further addressed by comparing it with a long period grating (LPG) fiber-optic sensor, which claims highly efficient core to cladding mode coupling. This study presents a new concept for the construction of a high-performance and cost-effective EW-based sensor system.

