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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
What is the Immune System?01:38

What is the Immune System?

Overview
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1 diabetes is an...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...

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Related Experiment Video

Updated: Jun 22, 2026

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry
12:36

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

Published on: June 26, 2018

Challenges for the autoimmunologist.

Torsten Matthias1, Yehuda Shoenfeld

  • 1AESKU.KIPP INSTITUTE, Mikroforum Ring, 355234, Wendelsheim, Germany.

Clinical Reviews in Allergy & Immunology
|June 25, 2009
PubMed
Summary
This summary is machine-generated.

The International Congress of Autoimmunity fosters global research and training. This special journal volume compiles key findings and challenges in autoimmunity, serving as a vital resource for researchers.

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Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies
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Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies

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Last Updated: Jun 22, 2026

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Area of Science:

  • Autoimmunity research
  • Immunology
  • Clinical research

Background:

  • The International Congress of Autoimmunity convenes biennially to advance interdisciplinary and international research in autoimmunity.
  • The 2008 Congress in Porto, Portugal, led to a special journal volume featuring investigator-submitted papers.
  • A satellite meeting focused on specific challenges for autoimmunologists.

Discussion:

  • This collection aims to consolidate recent advancements and ongoing challenges in the field of autoimmunity.
  • It highlights the importance of international collaboration in understanding and treating autoimmune diseases.
  • The publication serves as a platform for disseminating cutting-edge research and fostering further scientific dialogue.

Key Insights:

  • Compilation of key research papers from the 2008 Congress of Autoimmunity.
  • Focus on specific challenges and advancements in the field of autoimmunity.
  • Provides a valuable resource for the autoimmunity research community.

Outlook:

  • Encourages continued interdisciplinary and international collaboration in autoimmunity research.
  • Aims to facilitate training opportunities and knowledge exchange for autoimmunologists.
  • Serves as a foundational resource for future research directions in autoimmunity.