Serum markers in pre-eclampsia

Area of Science:

• Obstetrics and Gynecology
• Maternal-Fetal Medicine
• Clinical Diagnostics

Background:

• Preeclampsia is a major global cause of maternal and neonatal mortality.
• Affecting approximately 10% of pregnancies, it's typically diagnosed late in gestation.
• Understanding etiology and pathogenesis is key for prevention and risk prediction.

Purpose of the Study:

• To review current diagnostic tests for preeclampsia.
• To explore methods for predicting high-risk pregnancies.
• To evaluate tests for hypertensive disorders in pregnancy.

Main Methods:

• Literature review of clinical, biophysical, and biochemical tests.
• Analysis of diagnostic accuracy and predictive value.
• Synthesis of current evidence on preeclampsia evaluation.

Main Results:

• Numerous tests exist for preeclampsia prediction and early detection.
• Tests vary in their clinical utility and predictive performance.
• No single test is universally adopted for all scenarios.

Conclusions:

• Effective preeclampsia management relies on timely and accurate diagnosis.
• Continued research into novel biomarkers and diagnostic strategies is warranted.
• Early identification of at-risk pregnancies can improve outcomes.