Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune checkpoint inhibitors and immunosuppressive tumor microenvironment: current challenges and strategies to overcome resistance.

Immunopharmacology and immunotoxicology·2025
Same author

Editorial: eDiagnostics and monitoring for precision endocrinology.

Frontiers in endocrinology·2023
Same author

Multi-omics and machine learning for the prevention and management of female reproductive health.

Frontiers in endocrinology·2023
Same author

Comparative Evaluation of Serum High-sensitivity C-Reactive Protein and Complete Hemogram Indices in Subjects with and without Apical Periodontitis: A Prospective Interventional Study.

Journal of endodontics·2022
Same author

Heme oxygenase-1 in osteosarcoma.

Journal of cancer research and therapeutics·2020
Same author

Serum iron, Folate, Ferritin and CD4 Count in HIV Seropositive Women.

Indian journal of clinical biochemistry : IJCB·2017
Same journal

A Study on the Prognosis of Patients with Sepsis or Septic Shock Based on Plasma Proenkephalin Levels: A Meta-Analysis.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026
Same journal

Potential time-sensitive biomarkers for the detection of acute mesenteric ischaemia: a systematic review of animal data.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026
Same journal

Tissue expression profiles of miR-6809 and miR-4753 in triple-negative breast cancer: Novel biomarkers of early detection and staging.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026
Same journal

Digital biomarkers in non-communicable diseases.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026
Same journal

Quantitative analysis of murine C-terminal alpha-1-antitrypsin peptides in experimental sepsis and their comparison with human sepsis peptide biomarkers.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026
Same journal

Depression and oxidative stress in pregnancy: a cross-sectional study of trimester-specific changes.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Serum markers in pre-eclampsia.

Simmi Kharb1

  • 1Department of Biochemistry, Pt. Bhagwat Dayal Sharma, Post Graduate Institute of Medical Science, Rohtak, India. simmikh@redimail.com

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
|June 26, 2009
PubMed
Summary
This summary is machine-generated.

Preeclampsia affects 10% of pregnancies, causing significant maternal and infant mortality. Early detection through various clinical, biophysical, and biochemical tests is crucial for managing this hypertensive disorder of pregnancy.

More Related Videos

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

Related Experiment Videos

Last Updated: Jun 22, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Clinical Diagnostics

Background:

  • Preeclampsia is a major global cause of maternal and neonatal mortality.
  • Affecting approximately 10% of pregnancies, it's typically diagnosed late in gestation.
  • Understanding etiology and pathogenesis is key for prevention and risk prediction.

Purpose of the Study:

  • To review current diagnostic tests for preeclampsia.
  • To explore methods for predicting high-risk pregnancies.
  • To evaluate tests for hypertensive disorders in pregnancy.

Main Methods:

  • Literature review of clinical, biophysical, and biochemical tests.
  • Analysis of diagnostic accuracy and predictive value.
  • Synthesis of current evidence on preeclampsia evaluation.

Main Results:

  • Numerous tests exist for preeclampsia prediction and early detection.
  • Tests vary in their clinical utility and predictive performance.
  • No single test is universally adopted for all scenarios.

Conclusions:

  • Effective preeclampsia management relies on timely and accurate diagnosis.
  • Continued research into novel biomarkers and diagnostic strategies is warranted.
  • Early identification of at-risk pregnancies can improve outcomes.