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Related Experiment Video

Updated: Jun 22, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Helping patients with depression achieve wellness.

Mark Hyman Rapaport1

  • 1Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, David Geffen School of Medicine, University of California Los Angeles, CA, USA.

The Journal of Clinical Psychiatry
|June 26, 2009
PubMed
Summary

Treatment goals for depression are evolving. While response and remission were once aims, achieving wellness—full restoration of functioning and quality of life—is now the focus for long-term recovery.

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Last Updated: Jun 22, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Area of Science:

  • Psychiatry and Mental Health
  • Clinical Psychology

Background:

  • Historically, treatment for depression focused on achieving response, defined as a significant reduction in symptoms.
  • Subsequent research highlighted that response alone was insufficient for sustained recovery, leading to remission (complete symptom elimination) as the primary treatment goal.
  • Emerging evidence suggests that remission may also not be sufficient for optimal patient outcomes.

Purpose of the Study:

  • To explore the evolution of treatment goals in depression management.
  • To advocate for the adoption of 'wellness' as the ultimate treatment objective in depression.
  • To identify strategies that can facilitate the achievement of wellness in patients with depression.

Main Methods:

  • Literature review and synthesis of research findings on depression treatment outcomes.
  • Analysis of the progression of treatment goals from response to remission to wellness.
  • Conceptualization of strategies to enhance patient functioning and quality of life.

Main Results:

  • The definition of successful depression treatment has progressively shifted over time.
  • Achieving response and remission are intermediate steps, not the final goals of effective depression care.
  • Wellness, encompassing the full restoration of premorbid functioning and quality of life, represents a more comprehensive and desirable treatment outcome.

Conclusions:

  • Elevating treatment goals to wellness is crucial for achieving lasting recovery and improved quality of life in depression.
  • Integrating objective measures into clinical practice is essential for accurately assessing progress towards wellness.
  • Collaborative therapeutic relationships, involving patients actively in their treatment, are key to successfully attaining wellness.