Related Experiment Video

Updated: Jun 22, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

Intralesional amphotericin B in a cat with refractory localised sporotrichosis

Isabella D F Gremião1, Tânia Maria P Schubach, Sandro A Pereira

  • 1Laboratory of Clinical Research on Dermatozoonosis in Domestic Animals, Evandro Chagas Clinical Research Institute/Oswaldo Cruz Foundation (Fiocruz), Av Brasil, 4365 - Manguinhos, 21045-900, Rio de Janeiro - RJ, Brazil. isabella.dib@ipec.fiocruz.br

Journal of Feline Medicine and Surgery
|June 26, 2009
PubMed

Related Concept Videos

Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...
Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...