{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics

Vítor L Sousa1, Serena Bellani, Maila Giannandrea

  • 1Department of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.

Summary

Alpha-synuclein influences actin dynamics, affecting neuronal function. Its A30P mutant disrupts the cytoskeleton, potentially contributing to Parkinson's disease pathogenesis.

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