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Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...

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Updated: Jun 22, 2026

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

Tissue engineering and its implications in dentistry.

Parimala Tyagi¹, Manpreet Kaur Dhindsa

¹Department of Pedodontia, People's Dental Academy, Karond Bhanpur Bypass Road, Bhopal 462010, India. drtyagip@gmail.com

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research

|June 26, 2009

Summary

This summary is machine-generated.

Tissue engineering offers innovative solutions for repairing damaged tissues and creating replacement organs. This review covers fundamental principles and common components of tissue engineering strategies, including passive and inductive approaches.

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Area of Science:

Biomedical Engineering
Regenerative Medicine

Background:

Tissue engineering is an emerging field focused on restoring tissue function.
Current limitations in organ transplantation necessitate alternative solutions.
Advancements in biomaterials and cell biology drive tissue engineering innovation.

Purpose of the Study:

To review the core principles of tissue engineering.
To outline the essential components used in tissue engineering strategies.
To provide examples of different tissue engineering approaches.

Main Methods:

Review of existing literature on tissue engineering principles.
Analysis of common materials and techniques used in the field.
Categorization of tissue engineering strategies into passive and inductive approaches.

Main Results:

Tissue engineering utilizes strategies to repair or replace damaged tissues and organs.
Key components include cells, scaffolds, and bioactive molecules.
Passive approaches (e.g., dental implants) and inductive approaches (e.g., molecular signaling) are primary methods.

Conclusions:

Tissue engineering holds significant promise for regenerative medicine.
Understanding the principles and components is crucial for developing new therapies.
Both passive and inductive strategies offer viable pathways for tissue regeneration.