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Misleading ECG appearance of AV block due to concealed AV nodal conduction caused by interpolated ventricular ectopic
Hasan Ari1, Selma Ari, Vedat Koca
1Department of Cardiology, Bursa Postgraduate Hospital, Bursa, Turkey. hasanari03@yahoo.com
Insights
Premature ventricular complexes can cause concealed conduction, leading to atrioventricular block. Metoprolol effectively treated a patient experiencing fatigue and palpitations due to this condition.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Concealed conduction, often due to interpolated ectopic impulses, affects atrioventricular (AV) node function.
- This can result in non-conduction or prolonged PR intervals of subsequent sinus beats due to AV conduction system refractoriness.
Observation:
- A 67-year-old male presented with exertional fatigue and palpitations.
- Electrocardiogram showed frequent premature ventricular complexes (PVCs) with right bundle branch block morphology.
- Holter monitoring revealed interpolated PVCs, progressive PR prolongation, and Mobitz type I atrioventricular block.
Findings:
- The patient's symptoms were directly linked to frequent interpolated PVCs causing concealed conduction and subsequent AV block.
- Treatment with metoprolol led to a significant reduction in PVCs and resolution of AV block and symptoms.
Implications:
- This case highlights the clinical significance of concealed conduction from PVCs in causing symptomatic AV block.
- Pharmacological management with beta-blockers can be effective in managing such conditions.
- Understanding this mechanism is crucial for diagnosing and treating arrhythmias involving AV nodal function.
Abstract:
Concealed conduction commonly occurs when a retrogradely conducted interpolated ectopic impulse enters the atrioventricular (AV) node; thus, the next sinus beat is not conducted to the ventricle or conducted with a prolonged PR interval because of increased refractoriness of AV conduction system. A 67-year-old man had complaints of exertional fatigue and palpitations at rest. His blood pressure was 110/70 mmHg and heart rate was 78 beats/min. Auscultation revealed a mild systolic murmur at the apex and an irregular rhythm. His electrocardiogram was normal, except for the presence of frequent premature ventricular complexes (PVC) of right bundle branch block morphology. Echocardiographic examination showed only grade-1 mitral regurgitation. Further evaluation with 24-h Holter monitoring showed frequent interpolated PVCs in bigeminal rhythm. Progressive prolongation of the PR interval was observed after each PVC, which ended with Mobitz type I AV block. The patient was treated with metoprolol which resulted in immediate and marked improvement in the symptoms. Control Holter recording showed very rare PVCs, without PR prolongation or AV block.
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