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Updated: Jun 22, 2026

Human Egg Maturity Assessment and Its Clinical Application
Published on: August 19, 2019
Constriction band syndrome occurring in the setting of in vitro fertilization and advanced maternal age
Brian Rinker1, Henry C Vasconez
1Division of Plastic Surgery, University of Kentucky, Lexington, Kentucky, USA.
Abstract:
The debate as to the pathogenesis of constriction band syndrome began with Hippocrates and continues today. The exogenous theory attributes the condition to entanglement of the fetus in the amniotic remnants following premature rupture of the amnion, which is in contrast to the endogenous, or genetic, mechanism.A case of constriction band syndrome in the setting of in vitro fertilization, where the child was genetically unrelated to the birth mother, is presented. Constriction band syndrome has been reported following amniocentesis and chorionic villus sampling, but it has not heretofore been presented in the setting of in vitro fertilization. In addition, the present case presents an opportunity to separate maternal from genetic factors and, possibly, shed some light on the etiology of the condition.
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