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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

Controlled assembly of bifunctional chimeric protein cages and composition analysis using noncovalent mass

Sebyung Kang1, Luke M Oltrogge, Chris C Broomell

  • 1Department of Chemistry & Biochemistry, Montana State University, Bozeman, Montana 59717, USA.

Journal of the American Chemical Society
|June 26, 2009
PubMed
Abstract

No abstract available in PubMed .

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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...

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