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Seroprevalence of mumps before inclusion of mumps vaccination in the Iranian expanded programme on immunization

M Avijgan1, R Habibian, S Kheiri

  • 1Department of Infectious and Tropical Diseases and Iranian Traditional Medicine Research Centre, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. avijgan@yahoo.com

Eastern Mediterranean Health Journal = La Revue De Sante De La Mediterranee Orientale = Al-Majallah Al-Sihhiyah Li-Sharq Al-Mutawassit
|June 27, 2009
PubMed

Insights

A study in Iran found nearly 20% of children aged 3-18 lacked mumps antibodies. Researchers recommend vaccinating 7-11 year olds to improve herd immunity.

Area of Science:

  • Immunology
  • Public Health
  • Pediatrics

Background:

  • Current measles, mumps, and rubella (MMR) vaccination targets in Iran are children at 12 months and 4-6 years.
  • A study was conducted in Shahrekord to assess mumps antibody seroprevalence in children aged 3-18 years.

Purpose of the Study:

  • To determine the need for booster vaccinations against mumps.
  • To identify non-immune children requiring vaccination to achieve herd immunity.

Main Methods:

  • Age-specific seroprevalence of mumps antibodies was studied in 338 children aged 3-18 years.
  • Seronegativity rates were analyzed across different age groups (7-11, 12-14, and 15-18 years).

Main Results:

  • Overall, 19.8% of the children studied were seronegative for mumps antibodies.
  • Seronegativity was highest in the 7-11 year age group (33.3%), followed by 12-14 years (20.5%), and 15-18 years (4.6%).

Conclusions:

  • Children aged 7-11 years represent a significant group lacking immunity to mumps.
  • Vaccinating this age group entering guidance school is recommended for the next five years to achieve herd immunity.

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