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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Potassium Channel Activators01:20

Antiepileptic Drugs: Potassium Channel Activators

Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
Antiepileptic Drugs: Sodium Channel Blockers01:08

Antiepileptic Drugs: Sodium Channel Blockers

Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...

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Related Experiment Video

Updated: Jun 22, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
07:01

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

Managing epilepsy: issues in the elderly.

Richard A Marasco1, R Eugene Ramsay

  • 1Pharmaceutical Care and Management Services, Valdosta, GA, USA. rmarasco@seniorpharm.com

The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists
|June 27, 2009
PubMed
Summary
This summary is machine-generated.

Managing epilepsy in older adults requires careful consideration of health conditions and multiple medications. Pharmacist involvement is crucial for effective care planning and reducing adverse drug events in elderly epilepsy patients.

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Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture
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Published on: December 22, 2016

Related Experiment Videos

Last Updated: Jun 22, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
07:01

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Published on: May 16, 2019

Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

Area of Science:

  • Geriatric Medicine
  • Neurology
  • Clinical Pharmacy

Background:

  • Epilepsy treatment in the elderly presents unique challenges.
  • Comorbidities and polypharmacy complicate management.
  • Antiepileptic drug (AED) therapy requires careful monitoring.

Purpose of the Study:

  • To identify factors influencing epilepsy treatment in the elderly.
  • To outline strategies for AED discontinuation in seizure-free patients.
  • To develop a comprehensive epilepsy care plan for residents.

Main Methods:

  • Content derived from a live symposium.
  • Based on current clinical practice.
  • Informed by relevant research.

Main Results:

  • Elderly epilepsy management is complex due to comorbidities and polypharmacy.
  • Minimizing drug interactions and monitoring efficacy/toxicity are essential.
  • Pharmacist consultation is vital for optimizing treatment.

Conclusions:

  • Consultant pharmacists are integral to epilepsy care in nursing facilities.
  • Integration of pharmacists in care plan development is recommended.
  • Proactive management can improve outcomes for elderly epilepsy patients.