[Acute leukemia and generalized cytomegaly in a 10-year-old boy]

A case of acute myelomonocytic leukemia in a 10-year-old boy who received massive cytostatic therapy is described. At autopsy a picture of therapeutically determined pathomorphism and cytostatic disease with generalized cytomegalia and terminal staphylococcal sepsis was revealed. Multiple thrombosis of major venous trunks, necroses of the cecum and subtotal necrosis of the spleen were observed; this apparently was associated with generalized cytomegalia and massive cytostatic therapy. Peculiar features of the case were dystrophic changes in cytomegalic cells subjected to necrobiosis, which, probably, was due to cytostatic therapy.