Related Experiment Video
Updated: Jun 22, 2026
10:33
Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase
Published on: October 15, 2018
TET2 mutations in myelodysplasia and myeloid malignancies
1Department of Pathology, St Jude's Research Hospital, Memphis, TN, USA. charles.mullighan@stjude.org
Nature Genetics
|June 27, 2009
Abstract:
The genetic basis of myelodysplasia has long been enigmatic, with few common targets of mutation known. A new study reports common mutations in the TET2 gene in myelodysplasia and related myeloid malignancies, suggesting that TET2 has an important role in hematopoiesis and in the pathogenesis of this disease.
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