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Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
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Cinnamic aldehyde derived probes for the active site labelling of pathogenesis associated enzymes

Maximilian Pitscheider1, Stephan A Sieber

  • 1Center for Integrated Protein Science Munich CIPSM, Department of Chemistry and Biochemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.

Chemical Communications (Cambridge, England)
|June 27, 2009
PubMed

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Labeling DNA Probes

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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