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Fixing Double-strand Breaks02:04

Fixing Double-strand Breaks

The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
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Foundation trusts. Breaking free.

Helen Mooney

    The Health Service Journal
    |June 27, 2009
    PubMed
    Summary
    This summary is machine-generated.

    The foundation trust model, introduced five years ago, aimed to grant hospitals greater innovation freedom. Its impact and reception continue to be subjects of significant debate.

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    Area of Science:

    • Healthcare Management
    • Health Policy
    • Hospital Administration

    Background:

    • The foundation trust model was implemented in the UK's National Health Service (NHS) approximately five years ago.
    • Its introduction followed extensive debate regarding potential impacts on hospital autonomy and innovation.

    Purpose of the Study:

    • To evaluate the initial reception and perceived benefits of the foundation trust model.
    • To explore the expectations of stakeholders involved in the model's creation regarding hospital innovation.

    Main Methods:

    • Qualitative analysis of policy documents and stakeholder statements from the model's inception.
    • Review of early academic and media commentary on foundation trusts.

    Main Results:

    • The model generated considerable debate upon its introduction.
    • Key proponents anticipated increased flexibility and innovation opportunities for hospitals under this new structure.

    Conclusions:

    • The foundation trust model represented a significant shift in NHS governance, intended to foster innovation.
    • The initial period was characterized by both anticipation of enhanced autonomy and ongoing discussion about its implications.