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Whole-Body Nanoparticle Aerosol Inhalation Exposures
Published on: May 7, 2013
Workplace exposure to engineered nanoparticles
1Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Gruppe 4.5 Wirkung biologischer und chemischer Arbeitsstoffe, Berlin, Germany. plitzko.sabine@baua.bund.de
Inhalation Toxicology
|June 30, 2009
Summary
Workplace measurements of nanostructured materials like TiO(2) and nanofibers show no significant increase in particle number concentration with proper handling. However, agglomerates may be released during maintenance or system failures.
Area of Science:
- Occupational health and safety
- Materials science
- Environmental monitoring
Background:
- Nanostructured materials are increasingly used in various industries.
- Assessing potential workplace exposure to nanoparticles is crucial for worker safety.
- Existing measurement strategies may not fully differentiate between ambient and process-generated nanoparticles.
Purpose of the Study:
- To present measurement strategies and results from workplaces handling nanostructured materials.
- To evaluate nanoparticle exposure during the manufacturing and processing of specific nanomaterials.
- To develop a robust measurement approach considering ambient air and process emissions.
Main Methods:
- Measurements conducted in research labs and small-scale production facilities.
- Utilized scanning mobility particle sizers (Grimm) and concentration particle counters (TSI).
- Developed a strategy including ambient air monitoring and electron microscopy for agglomerate analysis and chemical composition.
Main Results:
- Demonstrated measurement results for TiO(2), nanofibers, ceramic nanopowders, and electrical industry nanostructured materials.
- Presented mean number concentrations of nanoparticles.
- Electron microscopy detected some particle agglomerates, despite no significant increase in overall nanoparticle numbers under proper handling.
Conclusions:
- Proper handling (e.g., closed systems, extractor hoods) minimizes nanoparticle release during routine operations.
- Nanostructured materials may be primarily released during non-routine activities like cleaning, maintenance, or operational failures.
- Further investigation into release during specific non-routine tasks is warranted.

