Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 22, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Gamma knife surgery for lymphocytic hypophysitis.

Dibyendu Kumar Ray1, Chun Po Yen, Mary Lee Vance

  • 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA.

Journal of Neurosurgery
|June 30, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of personalized exercogs for older adults care: A feasibility and single-arm study.

International journal of clinical and health psychology : IJCHP·2026
Same author

Multi-Center, Multi-National Outcomes Following Endoscopic Endonasal Resection of Nonfunctional Pituitary Adenomas.

Journal of neurological surgery. Part B, Skull base·2026
Same author

Reference Values of the Inventory of Callous-Unemotional Traits in Youth Populations: A Systematic Literature Review.

Clinical child psychology and psychiatry·2026
Same author

Determining the Magnitude of Surgery in Patients With Adult Scoliosis: A Systematic Review of the Role of Limited Fusions.

Global spine journal·2025
Same author

A contemporary, multiinstitutional analysis of transcription factor lineage in pituitary adenomas: comparative study of neuroimaging, histopathology, and clinical outcomes.

Journal of neurosurgery·2025
Same author

Predictors of biochemical remission after transsphenoidal surgery in a large cohort of acromegaly patients.

Pituitary·2024
Same journal

Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

Journal of neurosurgery·2026
Same journal

Surgical treatment of schwannomas around the tarsal tunnel: a case series of 40 patients and systematic review of the literature.

Journal of neurosurgery·2026
Same journal

Direct targeting for focused ultrasound thalamotomy in the treatment of movement disorders.

Journal of neurosurgery·2026
Same journal

Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

Journal of neurosurgery·2026
Same journal

Connectional anatomy of the cerebellum: dentate nucleus and cerebellar peduncles from a surgical perspective.

Journal of neurosurgery·2026
Same journal

Press releases in neurosurgery: is scientific accuracy compromised in public reporting of neurosurgery research?

Journal of neurosurgery·2026
See all related articles

Lymphocytic hypophysitis, a rare pituitary disorder, can be challenging to treat. Gamma Knife surgery (GKS) offers a viable solution for persistent cases, allowing patients to discontinue steroid therapy.

Area of Science:

  • Endocrinology
  • Neurosurgery
  • Immunology

Background:

  • Lymphocytic hypophysitis (LYH) is an uncommon autoimmune inflammatory condition affecting the pituitary gland, predominantly in women of childbearing age.
  • Clinical presentation often includes visual disturbances and pituitary enlargement due to inflammation.

Observation:

  • A case report details a patient with diplopia and significant pituitary enlargement, diagnosed with LYH via histopathology after transsphenoidal surgery.
  • The patient's condition was refractory to surgical resection and corticosteroid therapy, with symptoms recurring upon steroid withdrawal.

Findings:

  • Gamma Knife surgery (GKS) was performed on the sella and cavernous sinuses.
  • Following GKS, the patient achieved symptom resolution and was able to discontinue corticosteroid therapy without recurrence.

More Related Videos

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
07:22

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

Published on: April 11, 2025

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
11:45

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition

Published on: November 14, 2013

Related Experiment Videos

Last Updated: Jun 22, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
07:22

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

Published on: April 11, 2025

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
11:45

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition

Published on: November 14, 2013

  • Follow-up MRI confirmed no evidence of recurrent LYH.

    • Implications:

    • Gamma Knife surgery presents a promising treatment option for persistent or refractory lymphocytic hypophysitis.
    • This approach may offer a way to manage LYH effectively, reducing reliance on long-term corticosteroid treatment and its associated side effects.