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Updated: Jun 22, 2026
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High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
A new cerebroside from Gynura divaricata
Lei Chen1, Houquan Li, Hongtao Song
1Department of Pharmacy, Fuzhou General Hospital of Nanjing Military Region, Fuzhou, PR China.
Fitoterapia
|June 30, 2009
Summary
Researchers discovered a novel cerebroside in the aerial parts of Gynura divaricata DC. This new compound, a complex lipid, was successfully isolated and characterized from the plant material.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
- Organic Chemistry
Background:
- Gynura divaricata DC. is a plant species with a history of traditional medicinal use.
- The chemical constituents of Gynura divaricata DC. are of interest for potential pharmacological activities.
- Cerebrosides are a class of lipids known for their biological significance.
Purpose of the Study:
- To isolate and identify novel compounds from the aerial parts of Gynura divaricata DC.
- To characterize the structure of a newly discovered cerebroside.
Main Methods:
- Extraction of compounds from the aerial parts of Gynura divaricata DC.
- Chromatographic techniques for isolation (e.g., column chromatography, HPLC).
- Spectroscopic methods for structural elucidation (e.g., NMR, Mass Spectrometry).
Main Results:
- A new cerebroside was successfully isolated from Gynura divaricata DC.
- The chemical structure was determined as 1-O-beta-D-glucopyranosyl-(2S,3S,4R,10E)-2-[(2'R)-2'-hydroxyltricosanoyl-amino]-10-octadecene-1,3,4-triol.
- The isolation was performed on the aerial parts of the plant.
Conclusions:
- A novel cerebroside has been identified and structurally elucidated from Gynura divaricata DC.
- This finding contributes to the phytochemical knowledge of Gynura species.
- Further research may explore the biological activities of this newly isolated compound.
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