Related Experiment Video
Updated: Jun 22, 2026

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
Published on: November 16, 2011
BMI and hyperinsulinemia in children
Michael Vogeser1, Peter Schwandt, Gerda-Maria Haas
1Institute of Clinical Chemistry, University of Munich, Marchioninistr. 15, D-81377 Munich, Germany. Michael.Vogeser@med.uni-muenchen.de
Objectives:
Overweight is associated with hyperinsulinemia in adults and children. The aim of our study was to test if body mass index (BMI) alone or in combination with waist circumference (WC) predicts hyperinsulinemia in individual children.
Methods:
In 466 healthy German schoolchildren aged 7 to 12 years enrolled in the population based PEP Family Heart Study, anthropometric data, standard laboratory data and fasting serum insulin concentrations were assessed.
Results:
Among children with hyperinsulinemia (fasting serum insulin concentrations>85th age specific percentile), 56% were not overweight (BMI-for-age<85th percentile). Among overweight children, 54% were normoinsulinemic. Increased waist circumference (WC for age and gender>85th percentile) was not a better predictor of hyperinsulinemia, neither alone nor in combination with BMI.
Conclusion:
Overweight and abdominal obesity are poor indicators of hyperinsulinemia in individual German school children aged 7 to 12 years. Insulin measurement seems to be necessary to reliably detect hyperinsulinemia.
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Obesity
Hyperglycemia
Diabetes Mellitus: Introduction
Diabetes Mellitus: Type 2 and Gestational

