Related Experiment Video
Updated: Jun 22, 2026

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Acute massive cerebral infarctions treated with hemodialysis
Kessarin Panichpisal1, Takamitsu Saigusa, Sharmila Sehli
1Department of Neurology, State University of New York, Downstate Medical Center, Brooklyn, New York 11203, USA. kessarin100@hotmail.com
Daily hemodialysis (HD) may help manage severe cerebral edema in patients experiencing massive cerebral infarction, even those with Down syndrome and end-stage renal disease. This case suggests HD as a potential stroke treatment strategy.
Area of Science:
- Nephrology
- Neurology
- Cardiology
Background:
- Down syndrome and end-stage renal disease (ESRD) present complex medical challenges.
- Massive pericardial effusion can lead to significant cardiac compromise and systemic complications.
Observation:
- A 19-year-old woman with Down syndrome and ESRD presented with stroke symptoms and massive pericardial effusion.
- Initial presentation included acute right middle cerebral artery infarction with severe cerebral edema, which improved with daily hemodialysis (HD).
- Subsequent embolic infarctions occurred in multiple cerebral artery distributions, again showing dramatic cerebral edema reduction with frequent HD.
Findings:
- Daily hemodialysis (HD) demonstrated efficacy in reducing severe cerebral edema associated with acute ischemic stroke.
- The patient experienced significant neurological improvement in cerebral edema management through frequent HD sessions.
- Case suggests potential benefits of daily HD in managing massive cerebral infarction, despite existing controversies.
Implications:
- Daily HD may represent an alternative therapeutic strategy for managing massive cerebral infarction and associated cerebral edema.
- Further research is warranted to explore the role and safety of dialysis in acute stroke management.
- This case highlights the complex interplay between renal disease, cardiac complications, and neurological events.
More Related Videos
Related Concept Videos
Hemodialysis I: Introduction
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute Kidney Injury V: Interprofessional Care
Ischemic Stroke ll: Pathophysiology
Hemodialysis II: Procedure and Complications
Continuous Renal Replacement Therapy

