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Updated: Jun 22, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity

Mariusz P Gajewski1, Howard Beall, Mark Schnieder

  • 1Department of Biomedical and Pharmaceutical Sciences, The University of Montana, Missoula, MT 59812, USA.

Bioorganic & Medicinal Chemistry Letters
|June 30, 2009
PubMed
Summary

Dimeric analogs of Anthracenyl Isoxazole Amides (AIMs) show promise as anti-tumor agents. Dimer 6 demonstrated the highest efficacy against human glioma cells (SNB-19) in this compound class.

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