Related Experiment Video
Updated: Jun 22, 2026

Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
A paradigm shift: volume augmentation or 'inflation' to obtain optimal cosmetic results
Craig D Lewis1, Julian D Perry
1Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Purpose Of Review:
In the last several years, surgeons have increasingly realized the importance of volume loss as a central mechanism of facial aging. New, innovative techniques incorporate volume augmentation, or inflation, to improve cosmetic outcomes.
Recent Findings:
Previous rejuvenative facial surgical techniques focused on the removal of excess, lax tissues. In addition to tissue laxity and descent, volume loss significantly contributes to the appearance of facial aging in most patients. Volume loss, or deflation, affects all facial layers, including the skin, deep soft tissue, and bone. A variety of new, innovative surgical and nonsurgical techniques specifically address volume deficiencies in the brow, periorbita, and midface. Volume augmentation directly counteracts volume loss, a key feature of facial aging, and offers surgeons a powerful tool to improve cosmetic results.
Summary:
In addition to the excision or repositioning of lax or prolapsed tissues, surgeons must assess and treat facial volume loss to optimize cosmetic outcomes.
