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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Related Experiment Video

Updated: Jun 22, 2026

Studying Orthodontic Tooth Movement in Mice
07:17

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

Medication and tooth movement.

Anmol S Kalha1

  • 1Institute of Dental Studies and Technologies, Modinagar, India.

Evidence-Based Dentistry
|June 30, 2009
PubMed
Summary
This summary is machine-generated.

This review found significant variability in study designs and methods, making it difficult to compare results on how medications affect orthodontic tooth movement. More well-designed studies are needed to clarify these effects.

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Last Updated: Jun 22, 2026

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Area of Science:

  • Orthodontics
  • Pharmacology
  • Biomedical Engineering

Background:

  • A systematic review was conducted to evaluate the impact of medications on orthodontic tooth movement.
  • Studies were included if they involved animal or clinical trials with at least five subjects per group, used drugs affecting bone physiology, and detailed force application and measurement of tooth movement.

Discussion:

  • The review identified numerous issues with the quality of existing literature, predominantly from animal studies.
  • Variability in experimental design, animal models, drug administration, and force application hindered data comparison.

Key Insights:

  • Forty-nine studies were included in the review.
  • Significant heterogeneity across studies made direct comparisons challenging.
  • The quality of data presented in the reviewed literature was found to be problematic.

Outlook:

  • There is a clear need for more rigorously designed studies to investigate the effects of various medications on orthodontic tooth movement.
  • Standardized methodologies are required for future research in this area.