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Studying Proteolysis of Cyclin B at the Single Cell Level in Whole Cell Populations
10:54

Studying Proteolysis of Cyclin B at the Single Cell Level in Whole Cell Populations

Published on: September 17, 2012

Post-translational modification and stability of low molecular weight cyclin E

B B Mull1, J Cox, T Bui

  • 1Department of Experimental Radiation Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.

Oncogene
|June 30, 2009
PubMed
Summary

Researchers identified that phosphorylation at threonine 395 generates larger low molecular weight cyclin E isoforms. These isoforms remain stable in tumor and non-tumor cells, suggesting implications for cancer development and treatment.

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