Related Experiment Video
Updated: Jun 22, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
Loss of digits after trauma in a patient with systemic lupus erythematosus
Heidee Villanueva1, Marius Tijunelis, Sharon Shapiro
1Department of Emergency Medicine, Keck School of Medicine of the University of Southern California.
Abstract:
A 19-year-old female with Systemic Lupus Erythematosus (SLE) presented with ischemia of her left hand following trauma. Medical therapy was initiated but failed to improve her symptoms, and revision amputation was ultimately performed. The patient's final diagnosis was digital ischemia due to secondary Raynaud's Phenomenon (RP). The authors discuss diagnosis, complications, and treatment of this relatively uncommon disorder. The authors report this case in order to discuss how secondary RP can be complicated by ischemia and the multidisciplinary approach that needs to take place to prevent the latter from occurring.
Related Concept Videos
Diabetic Foot Ulcer
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
