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Published on: December 6, 2024

American psychiatric association

Walter Alexander

    P & T : a Peer-Reviewed Journal for Formulary Management
    |June 30, 2009
    PubMed

    Insights

    New atypical antipsychotics like iloperidone and asenapine show comparable efficacy to older drugs with fewer side effects for schizophrenia and bipolar disorder. Promising results also emerged for PTSD treatment in veterans using medication combined with virtual reality exposure therapy.

    Area of Science:

    • Psychiatry and Pharmacology
    • Mental Health Treatment Innovations

    Background:

    • Schizophrenia and bipolar disorder treatments often involve atypical antipsychotic medications.
    • Existing treatments may have significant side effect profiles.
    • Post-traumatic stress disorder (PTSD) in military veterans requires effective therapeutic approaches.

    Purpose of the Study:

    • To present efficacy and side-effect data for new atypical antipsychotic medications.
    • To explore novel treatment combinations for PTSD in veterans.

    Main Methods:

    • Presentation of clinical data on iloperidone and asenapine at the American Psychiatric Association's 161st Annual Meeting.
    • Review of preliminary results for combined medication and virtual reality exposure therapy for PTSD.

    Main Results:

    • New atypical antipsychotics (iloperidone, asenapine) demonstrated efficacy comparable to older agents.
    • Iloperidone and asenapine exhibited more favorable side-effect profiles in schizophrenia and bipolar disorder.
    • Medication combined with virtual reality exposure therapy showed promise for treating PTSD in veterans.

    Conclusions:

    • Newer atypical antipsychotics offer a potentially improved therapeutic option for schizophrenia and bipolar disorder.
    • Combined pharmacotherapy and virtual reality exposure therapy represent a promising avenue for PTSD treatment in veterans.

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