Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

In Vitro Fertilization

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Is MTHFR 677 C>T Polymorphism Clinically Important in Polycystic Ovarian Syndrome (PCOS)? A Case-Control Study, Meta-Analysis and Trial Sequential Analysis.

PloS one·2016

Same author

Androgen receptor CAG repeats length polymorphism and the risk of polycystic ovarian syndrome (PCOS).

PloS one·2013

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 22, 2026

Human Blastocyst Biopsy and Vitrification

Human Blastocyst Biopsy and Vitrification

Published on: July 26, 2019

Selective single blastocyst transfer study: 604 cases in 6 years.

Nirmala Sadasivam¹, Narayanan M Sadasivam

¹Department of Infertility Medicine, Maaruthi Medical centre and Hospitals, Erode, Tamilnadu, India.

Journal of Human Reproductive Sciences

|June 30, 2009

Summary

Single blastocyst transfer (SBT) is a credible method for selected fertile patients, achieving a 64% overall pregnancy rate. Grade I blastocyst transfer showed higher success rates, indicating its potential in assisted reproductive technology.

Keywords:

Ovarian hyper stimulation syndrome (OHSS)single blastocyst transfer (SBT)single embryo transfer (SET)

More Related Videos

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis

Published on: September 7, 2021

Related Experiment Videos

Last Updated: Jun 22, 2026

Human Blastocyst Biopsy and Vitrification

Human Blastocyst Biopsy and Vitrification

Published on: July 26, 2019

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis

Published on: September 7, 2021

Area of Science:

Reproductive Medicine
Embryology
In Vitro Fertilization (IVF)

Background:

Single blastocyst transfer (SBT) is increasingly adopted in assisted reproductive technology to improve pregnancy outcomes and reduce multiple gestations.
Patient selection is crucial for optimizing SBT success rates, particularly in high-fertile groups.

Purpose of the Study:

To evaluate the clinical credibility and success rates of the single blastocyst transfer (SBT) method.
To assess the efficacy of SBT in a carefully selected group of patients with high fertility potential.

Main Methods:

Retrospective analysis of 604 single blastocyst transfer (SBT) cases.
Data collected from a private Fertility research centre between June 2000 and June 2006.
Inclusion criteria: women aged 28–42 years with 6–12 fertilized eggs.

Main Results:

Clinical pregnancy rates were 46.6% for Grade I blastocyst transfers and 17.4% for Grade II blastocyst transfers.
The overall pregnancy rate achieved with SBT was 64%.
Pregnancy loss rate, including early and late fetal wastage, was 11.06%.

Conclusions:

Single blastocyst transfer (SBT) demonstrates significant credibility as a method of choice for selected, highly fertile patients.
The quality of the blastocyst (Grade I vs. Grade II) significantly impacts clinical pregnancy rates.
SBT offers a viable option for achieving successful pregnancies while potentially minimizing risks associated with multiple gestations.