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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
An operationally simple colorimetric assay of hyaluronidase activity using cationic gold nanoparticles
Jung-Won Kim1, Joong Hyun Kim, Sang Jeon Chung
1BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yuseong-gu, Daejeon 305-600, South Korea.
The Analyst
|June 30, 2009
Abstract:
An operationally simple colorimetric way for measuring hyaluronidase activity was developed using cysteamine-bound gold nanoparticles. The addition of gold nanoparticles into hyaluronidase-containing solutions resulted in color changes, which could easily be observed with the naked eye or a UV/Vis spectrophotometer.
