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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

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Related Experiment Video

Updated: Jun 22, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

[Elderly onset rheumatoid arthritis].

Anna Filipowicz-Sosnowska1, Robert Rupiński

  • 1Department of Rheumatology, Eleonora Reicher Rheumatology Institute, Warszawa, Poland. filipowicz@ir.ids.pl

Polskie Archiwum Medycyny Wewnetrznej
|July 1, 2009
PubMed
Summary

Elderly-onset rheumatoid arthritis (EORA) presents differently than younger-onset RA (YORA), with distinct characteristics and outcomes, particularly in seropositive individuals. EORA can lead to more severe joint damage and functional decline compared to YORA.

Area of Science:

  • Rheumatology
  • Geriatric Medicine
  • Immunology

Context:

  • Rheumatoid arthritis (RA) onset in individuals aged 60 and older (elderly-onset rheumatoid arthritis, EORA) exhibits distinct clinical and prognostic features compared to younger-onset RA (YORA).
  • Understanding these differences is crucial for accurate diagnosis and tailored treatment strategies in the aging population.
  • Existing literature highlights variations in presentation, disease activity, and long-term outcomes between EORA and YORA.

Purpose:

  • To review and synthesize available data comparing the clinical presentation, disease activity, radiographic damage, and functional outcomes of EORA versus YORA.
  • To elucidate the specific differences observed between seropositive and seronegative EORA patients.
  • To provide a comprehensive overview of the current understanding of EORA and its unique characteristics.

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Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients
07:44

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients

Published on: July 14, 2023

Related Experiment Videos

Last Updated: Jun 22, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients
07:44

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients

Published on: July 14, 2023

Summary:

  • EORA differs from YORA with a more balanced sex distribution, acute onset, frequent large joint involvement (especially shoulders), and higher initial disease activity.
  • Longitudinal data indicate greater disease activity, more severe radiographic damage, and functional decline in seropositive EORA patients compared to YORA.
  • Seronegative EORA patients show a milder disease course and better outcomes, often presenting with polymyalgia rheumatica or remitting seronegative symmetrical synovitis with pitting edema.

Impact:

  • Highlights the importance of considering age at onset in RA patient stratification and management.
  • Suggests potential differences in treatment response and long-term prognosis based on age and serological status.
  • Informs clinical practice and future research directions for optimizing care in elderly RA patients.