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Updated: Jun 22, 2026

Simultaneous Distinction of Monospecific and Mixed DFS70 Patterns During ANA Screening with a Novel HEp-2 ELITE/DFS70 Knockout Substrate
Published on: January 17, 2018
[Clinically asymptomatic antiphospholipid antibodies--diagnostic and therapeutic problems]
Krystyna Zawilska1, Agata Lehmann-Kopydłowska
1Coagulation Laboratory, Department of Hematology, Medical University, Poznań, Poland. k.zawilska@interia.pl
Abstract:
The presence of asymptomatic antiphospholipid antibodies (aAPA) creates many difficult diagnostic and clinical problems - they might be a cause either of incorrect hemorrhagic diathesis recognition or an unnecessary anticoagulant therapy. Patients with aAPA should be counseled individually regarding potential thrombotic and/or obstetric complications. An increased risk of these complications is particularly high when lupus anticoagulant (LAC) and IgG anti-beta2 glycoprotein antibodies coexist. The approaches to the diagnosis and management of treatment of patients with aAPA are also discussed.
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