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Related Experiment Video

Updated: Jun 22, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

[Neuromodulation for treatment for neurogenic bowel dysfunction].

Guang Fu¹, Li-min Liao, Zhen Lü

¹Department of Urology, China Rehabilitation Research Center, Rehabilitation School of Capital Medical University, Beijing 100068, China.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]

|July 1, 2009

Summary

Neuromodulation, including sacral and dorsal nerve stimulation, shows promise for treating neurogenic bowel dysfunction in spinal cord injury patients. Further research is needed to identify optimal candidates for these treatments.

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Area of Science:

Neurology
Gastroenterology

Context:

Neurogenic bowel dysfunction (NBD) is a common complication of spinal cord injury (SCI).
NBD significantly impacts patients' quality of life and functional independence.

Purpose:

To evaluate the efficacy of neuromodulation techniques for NBD in SCI patients.
Investigate sacral neuromodulation (SNM) and dorsal penile/clitoral nerve neuromodulation (DPN/DCN) for NBD treatment.

Summary:

A study involving 9 SCI patients with NBD assessed SNM and DPN/DCN.
Significant improvements in Wexner constipation scores were observed post-treatment.
One patient showed continuous improvement with permanent neuromodulation implantation.

Impact:

Neuromodulation may offer a viable treatment option for select NBD patients.
Current research highlights the need for predictive markers to identify suitable candidates.
High-quality studies are essential to validate the long-term effectiveness of these interventions.