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Pelvic actinomycosis confirmed after surgery: single center experience
Min H Choi1, Dae G Hong, Won J Seong
1Department of Obstetrics and Gynecology, Kyungpook National University School of Medicine, Daegu, Korea.
Archives of Gynecology and Obstetrics
|July 1, 2009
Summary
Pelvic actinomycosis diagnosis does not require considering intrauterine device use. Shorter, high-dose antibiotic therapy is effective for treating this condition.
Area of Science:
- Gynecology
- Infectious Diseases
- Surgical Pathology
Background:
- Pelvic actinomycosis is a rare, chronic granulomatous infection.
- It can mimic pelvic malignancy, complicating diagnosis and treatment.
Purpose of the Study:
- To review surgically confirmed cases of pelvic actinomycosis.
- To summarize key clinical and diagnostic features.
- To evaluate treatment outcomes and recurrence rates.
Main Methods:
- Retrospective review of 16 patients surgically treated for pelvic actinomycosis (1998-2006).
- Analysis of clinical presentation, diagnostic findings, and treatment regimens.
- Correlation of intrauterine device (IUD) use with disease presentation.
Main Results:
- 75% of patients used IUDs for an average of 5.2 years.
- Elevated white blood cell count, neutrophil percentage, CRP, and CA 125 were common.
- CT scans suggested malignancy in 50% of evaluated cases.
- All patients underwent surgery; treatment included IV and oral antibiotics.
- One case of ureter obliteration occurred preoperatively; no recurrences were observed.
Conclusions:
- IUD use is not a prerequisite for pelvic actinomycosis diagnosis.
- Distinguishing pelvic actinomycosis from malignancy requires diverse diagnostic methods, including imaging.
- Shorter courses of high-dose antibiotic therapy appear sufficient for treatment.