Related Experiment Video
Updated: Jun 22, 2026

08:27
Bronchoalveolar Lavage Exosomes in Lipopolysaccharide-induced Septic Lung Injury
Published on: May 21, 2018
Playing saxophone induced diffuse alveolar hemorrhage: a case report
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, St Martin De Porres Hospital, Chiayi, Taiwan.
Irish Journal of Medical Science
|July 1, 2009
Summary
Playing the saxophone for extended periods can cause diffuse alveolar hemorrhage (DAH), a condition similar to exercise-induced pulmonary hemorrhage (EIPH). This case resolved spontaneously without medical intervention.
Area of Science:
- Pulmonary Medicine
- Respiratory Physiology
Background:
- The blood-gas barrier's thinness is crucial for gas exchange but makes it vulnerable to mechanical stress from increased capillary pressure.
- Exercise-induced pulmonary hemorrhage (EIPH) is common in horses and suspected in humans.
Observation:
- A healthy 65-year-old male experienced diffuse alveolar hemorrhage (DAH) after playing the saxophone continuously for 6 hours.
- Symptoms included hemoptysis, crackles, and bilateral radiographic infiltrates.
Findings:
- High-resolution computed tomography confirmed DAH.
- Bronchoscopy revealed bilateral bronchial abnormalities, and histopathology of bronchoalveolar lavage supported the diagnosis.
Implications:
- This is the first reported instance of DAH induced by saxophone playing.
- The condition followed a benign course, resolving spontaneously without medical treatment.
Related Concept Videos
Atelectasis II: Pathophysiology
Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Pneumothorax II: Pathophysiology
Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
Pneumothorax-II
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
Pneumothorax-I
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Respiratory System Abnormal Finding I: Inspection and Percussion
Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Acute Respiratory Failure-II
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
