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Updated: Jun 22, 2026

Rat Model of Blood-brain Barrier Disruption to Allow Targeted Neurovascular Therapeutics
Published on: November 30, 2012
[Leningrad blockade and its medical implications. Part 1]
Abstract:
Medical consequences of Leningrad blockade are considered from the standpoint of modern science. Pathologies acquired by blockade survivors are regarded as extreme polymorbid conditions caused by combined effect of prolonged psychemotional stress, largest-scale famine, and hypothermia responsible for undermining vital functions. Special emphasis is laid on the role of nervous system dysregulation in the development of many diseases. The influence of physiological and pathological stress on the outcome of alimentary dystrophia is discussed in the psychosomatic context. Pathogenesis of dystrophia and Leningrad hypertension is analysed. Mechanisms of survival and rehabilitation in subjects with persistent traces of blockade pathology are considered.
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