Related Experiment Video
Updated: Jun 22, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
[Meta-analysis on the relationship between colorectal cancer and Helicobacter pylori infection]
Yan Zhang1, Chang Gao, Jing-Hua Zhai
1School of Public Health, Jining Medical University, Jining 272013, China.
Objective:
Analyzing all the related studies that have been published in the world to evaluate the relationship between colorectal cancer (including colorectal adenomas) and Helicobacter pylori infection by means of Meta-analysis.
Methods:
To analyze the 14 references consistent with inclusion criteria by reviewing manager 4.2, calculating the odds ratio and 95% confidence interval, then drawing funnel plot. Results The total sample size is 3165, cases and controls are 1330 and 1835, respectively. The pooled OR is 1.36, and 95% confidence interval 1.01, 1.82. The graphical funnel plot appearing asymmetrical, but analyzing by sensitivity analysis and fail-safe number calculation. The results are affected by publication bias.
Conclusion:
The results of our Meta-analysis show that Helicobacter pylori infection is a possible risk of colorectal cancer.
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