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10:56
A Novel Three-dimensional Flow Chamber Device to Study Chemokine-directed Extravasation of Cells Circulating under Physiological Flow Conditions
Published on: July 15, 2013
Extravasation injuries
R E C Rose1, R Felix, A Crawford-Sykes
1Division of Orthopaedics, Department of Surgery, Radiology, Anaesthesia and Intensive Care, The University of the West Indies, Kingston 7, Jamaica. West Indies. recrose@hotmail.com
The West Indian Medical Journal
|July 2, 2009
Summary
Extravasation from intravenous infusions can cause severe tissue damage. Delays in recognizing and treating these leaks increase patient morbidity, highlighting the need for a standardized treatment protocol.
Area of Science:
- Plastic Surgery
- Trauma Management
- Infusion Therapy
Background:
- Extravasation injuries from intravenous infusions pose significant risks.
- Delayed recognition and treatment exacerbate tissue damage and patient morbidity.
Purpose of the Study:
- To evaluate treatment timing and modalities for extravasation injuries.
- To assess the sequelae of extravasation injuries and identify factors influencing outcomes.
Main Methods:
- Retrospective chart review of 12 patients treated for extravasation injuries.
- Data collected included patient demographics, extravasated agent, treatment, necrosis interval, and hospital stay.
Main Results:
- Eleven of 12 patients developed skin necrosis, with necrosis intervals ranging from 12 hours to three weeks.
- Delayed discontinuation of infusion (12-22 hours) was observed in five patients.
- Ten patients required an average of 31 additional hospital days for injury management.
Conclusions:
- Extravenous leaks can lead to severe tissue damage.
- Prompt recognition and treatment are crucial to minimize morbidity.
- A standardized protocol for extravasation management is recommended.
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