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A Novel Three-dimensional Flow Chamber Device to Study Chemokine-directed Extravasation of Cells Circulating under Physiological Flow Conditions

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Extravasation injuries.

R E C Rose¹, R Felix, A Crawford-Sykes

¹Division of Orthopaedics, Department of Surgery, Radiology, Anaesthesia and Intensive Care, The University of the West Indies, Kingston 7, Jamaica. West Indies. recrose@hotmail.com

The West Indian Medical Journal

|July 2, 2009

Summary

This summary is machine-generated.

Extravasation from intravenous infusions can cause severe tissue damage. Delays in recognizing and treating these leaks increase patient morbidity, highlighting the need for a standardized treatment protocol.

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Area of Science:

Plastic Surgery
Trauma Management
Infusion Therapy

Background:

Extravasation injuries from intravenous infusions pose significant risks.
Delayed recognition and treatment exacerbate tissue damage and patient morbidity.

Purpose of the Study:

To evaluate treatment timing and modalities for extravasation injuries.
To assess the sequelae of extravasation injuries and identify factors influencing outcomes.

Main Methods:

Retrospective chart review of 12 patients treated for extravasation injuries.
Data collected included patient demographics, extravasated agent, treatment, necrosis interval, and hospital stay.

Main Results:

Eleven of 12 patients developed skin necrosis, with necrosis intervals ranging from 12 hours to three weeks.
Delayed discontinuation of infusion (12-22 hours) was observed in five patients.
Ten patients required an average of 31 additional hospital days for injury management.

Conclusions:

Extravenous leaks can lead to severe tissue damage.
Prompt recognition and treatment are crucial to minimize morbidity.
A standardized protocol for extravasation management is recommended.