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Updated: Jun 22, 2026

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
Published on: January 19, 2019
[Scientific basis for complex anti-cancer program in area containing uranium-extracting enterprises]
Abstract:
The authors studied oncologic morbidity and mortality in area containing Navoisky mining metallurgy enterprise in Uzbekhistan. Evidence is that workers engaged into the main process in the enterprise and over at least 60% of working time subjected to occupational carcinogens have oncologic risk over 10 times exceeding that in the reference group. Workers engaged into the auxiliary processes and periodically subjected to occupational carcinogens over at most 40% of working time have relative oncologic risk ratio equal to 3. Oncologic morbidity in the workers having no direct exposure to occupational carcinogens is at most 2 times higher than that of general population. The authors specified and justified a goal-oriented complex anti-cancer program in the enterprise, for improving the activities of its oncologic service.
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