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Polymicrogyria in standard poodles.

C Jurney¹, J Haddad, N Crawford

¹Neurology Department, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. cjurney@vet.upenn.edu

Journal of Veterinary Internal Medicine

|July 2, 2009

Summary

This summary is machine-generated.

Polymicrogyria in Standard Poodles presents with cortical blindness and neurological issues. This study details clinical, EEG, and imaging findings, noting a wider age range and less hydrocephalus than previously reported.

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Area of Science:

Veterinary Neurology
Comparative Pathology

Background:

Polymicrogyria is a brain malformation characterized by excessive small, disorganized gyri.
This condition affects canine breeds, including Standard Poodles, and cattle.

Observation:

Clinical signs in affected poodles included cortical blindness, gait disturbances, and behavioral changes.
Magnetic resonance imaging revealed disorganized gyri, particularly evident on T2-weighted dorsal plane images.
Electroencephalography (EEG) demonstrated epileptiform discharges consistent with complex partial motor seizures.

Findings:

Five Standard Poodles with confirmed polymicrogyria were analyzed retrospectively.
Occipital lobe involvement was consistent across all cases, with other lobes affected in some.
Compared to prior reports, these cases showed a broader age distribution (7 weeks to 5 years) and reduced incidence of hydrocephalus.

Implications:

This research expands the understanding of polymicrogyria's presentation and variability in Standard Poodles.
Findings aid in diagnosing and managing neurological disorders in affected dogs.
Highlights the importance of advanced imaging and EEG in characterizing canine brain malformations.