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Updated: Jun 22, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
[Application of fibreoptic endoscope in evaluation of swallowing]
Bi Qiang1, Xing-de Tian, Hua Wang
1Department of Otorhinolaryngology Head and Neck Surgery, Jingzhou First Hospital, Yangtze University, Jingzhou, Hubei 434000, China. qbmy1999@yahoo.com.cn
Objective:
To investigate the effect of fibreoptic endoscopic evaluation of swallowing (FEES) in the assessment of dysphagia.
Methods:
Fifty-two patients with neurogenic dysphagia underwent FEES and videofluoroscopy (VF) within a 2-day period. The results obtained were compared.
Results:
FEES with all consistencies revealed premature leakage in 48.1%, pooling in 75.0%, penetration in 69.2%, and aspiration in 55.8%, silent aspiration in 28.8% of patients. VF revealed above items in 44.2%, 63.5%, 57.7%, 46.2%, 21.2%, respectively. The FEES was then measured against the VF for sensitivity, specificity, positive predictive value, and negative predictive value. FEES showed higher sensibility and negative coincidence rate of penetration (90.0%, 81.3%), aspiration (87.5%, 87.0%) and silent aspiration (90.9%, 97.3%). According to the severity, the dysphagia in patients was classified into no penetration, penetration, aspiration and silent aspiration. A weighted Kappa value of 0.713 signified "substantial" agreement between the two tests.
Conclusions:
FEES is an effective and valuable tool for evaluating oropharyngeal dysphagia, and is helpful in guiding the patients for diet and rehabilitation.
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