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Related Experiment Video

Updated: Jun 22, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Blood-related proteomics.

Giancarlo Liumbruno1, Angelo D'Alessandro, Giuliano Grazzini

  • 1Italian National Blood Centre, Istituto Superiore di Sanità, Rome, Italy.

Journal of Proteomics
|July 2, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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See all related articles

Blood proteomics offers new insights into blood components like plasma and cells. This field is advancing rapidly, improving blood banking quality control and understanding molecular mechanisms.

Area of Science:

  • Proteomics
  • Hematology
  • Biochemistry

Background:

  • Blood-related proteomics is an emerging field with increasing data availability.
  • Research has focused on understanding protein complexity in plasma and blood cells.
  • Previous work has laid the groundwork for current proteomic investigations.

Purpose of the Study:

  • To review the current knowledge in blood-related proteomics.
  • To present the main advancements in proteomic investigations chronologically.
  • To explore the future potential of proteomics in blood research and blood banking.

Main Methods:

  • Review of existing literature on blood proteomics.
  • Chronological presentation of key proteomic studies on blood components.

Related Experiment Videos

Last Updated: Jun 22, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

  • Discussion of prospective proteomic applications.

    • Main Results:

    • Significant strides have been made in proteomic analysis of red blood cells, platelets, plasma, and white blood cells.
    • Proteomics can be applied to optimize blood banking processes, including collection, pathogen inactivation, and storage.
    • The field has evolved from basic research to a sensitive tool for molecular insights and quality control.

    Conclusions:

    • Proteomics provides a powerful lens for understanding blood and its components at a molecular level.
    • Proteomic tools are valuable for establishing new quality parameters in blood banking.
    • The future of blood proteomics may involve a shift towards donor-centric analysis.