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Updated: Jun 22, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Multiple giant coronary artery aneurysms
Rammohan Marla1, Rachel Ebel, Marcus Crosby
1Division of Cardiothoracic Surgery, Clement Zablocki VA Medical Center, Milwaukee, Wisconsin 53295, USA.
Insights
Giant coronary artery aneurysms are rare, especially when affecting all three major coronary arteries. This case report details a successful surgical treatment for such a rare condition involving the right, left circumflex, and left anterior descending arteries.
Area of Science:
- Cardiology
- Vascular Surgery
- Medical Case Reports
Background:
- Coronary artery aneurysms (CAAs) are uncommon vascular abnormalities.
- Giant coronary artery aneurysms (GCAAs) are exceedingly rare, posing significant clinical challenges.
Observation:
- A patient presented with giant aneurysms involving the right coronary artery (RCA), left circumflex artery (LCx), and left anterior descending artery (LAD).
- This presentation represents a unique confluence of GCAAs across all three major epicardial coronary arteries.
Findings:
- Surgical intervention was successfully employed to manage the extensive GCAAs.
- This case is the first documented instance of giant aneurysms affecting all three major coronary arteries simultaneously.
Implications:
- Highlights the possibility of concurrent GCAAs in all major coronary arteries.
- Underscores the efficacy of surgical management for complex GCAA cases.
- Contributes to the limited literature on extremely rare cardiovascular pathologies.
Abstract:
Coronary artery aneurysms are rare, and giant coronary artery aneurysms are even rarer. We describe a patient who had giant coronary aneurysms of the right, left circumflex, and left anterior descending coronary arteries. The aneurysms were successfully treated with surgical intervention. To the best of our knowledge, ours is the 1st report of giant aneurysms involving all 3 major coronary arteries.
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