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Esophageal Achalasia01:27

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Updated: Jun 22, 2026

Using a Whole-mount Immunohistochemical Method to Study the Innervation of the Biliary Tract in Suncus murinus
07:23

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Published on: June 15, 2017

Sphincter of Oddi and its dysfunction.

Prasad Seetharam1, Gabriel Rodrigues

  • 1Department of General Surgery, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association
|July 2, 2009
PubMed
Summary

The Sphincter of Oddi, often overlooked, is crucial in surgical practice for abdominal pain. Its dysfunction is a key condition requiring careful observation and management in patients.

Keywords:
Bile ductdysfunctionpancreassphincter of Oddisurgery

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Area of Science:

  • Gastroenterology
  • Surgical Anatomy
  • Hepatobiliary Surgery

Background:

  • The Sphincter of Oddi (SO) is a muscular valve controlling bile and pancreatic juice flow.
  • SO dysfunction is increasingly recognized as a cause of abdominal pain and biliary issues.
  • Traditionally confined to anatomy, the SO is now a focus in clinical and surgical practice.

Purpose of the Study:

  • To review conditions affecting the Sphincter of Oddi.
  • To specifically detail Sphincter of Oddi dysfunction (SOD) and its clinical relevance.
  • To provide a comprehensive literature review on SO-related diseases.

Main Methods:

  • Comprehensive literature search of medical databases.
  • Review of studies focusing on Sphincter of Oddi anatomy, physiology, and pathology.
  • Synthesis of findings related to disease states and dysfunction.

Main Results:

  • Various conditions impact the Sphincter of Oddi, leading to dysfunction.
  • Sphincter of Oddi dysfunction is linked to significant abdominal pain and hepatobiliary complications.
  • Literature highlights the growing importance of SO assessment in patient care.

Conclusions:

  • Sphincter of Oddi dysfunction is a critical clinical entity.
  • Understanding SO conditions is vital for effective patient management, especially for abdominal pain.
  • Further research and clinical attention to the SO are warranted.