Related Experiment Videos
Scirpentriol toxicity in young broiler chickens
A A Ademoyero1, P B Hamilton, J M Cullen
1College of Veterinary Medicine, North Carolina State University, Raleigh 27695-8401.
Poultry Science
|October 1, 1991
Summary
Scirpentriol (STO) mycotoxin negatively impacts broiler chickens, reducing growth and altering key blood markers. Its unique toxicological profile in chickens differs from related toxins like T-2 and DAS.
Area of Science:
- Mycotoxicology
- Poultry Science
- Veterinary Toxicology
Background:
- Scirpentriol (STO) is a trichothecene mycotoxin produced by Fusarium species.
- STO is the parent alcohol of acetylated scirpenol mycotoxins.
- Limited data exists on STO toxicity specifically in chickens.
Purpose of the Study:
- To describe the general toxicity of dietary Scirpentriol (STO) in broiler chickens.
- To determine the minimum effective dose (MED) for various toxic effects of STO.
- To differentiate STO toxicosis from that of T-2 toxin and diacetoxyscirpenol (DAS) in chickens.
Main Methods:
- Male broiler chickens were fed diets containing 0, 2, 4, 8, 16, or 32 micrograms/g of STO for 3 weeks.
- Growth rate, feed conversion efficiency, and organ weights were assessed.
- Serum biochemical parameters, including enzymes, proteins, electrolytes, and metabolites, were analyzed.
Main Results:
- The MED for reduced growth rate and increased gizzard weight was 4 micrograms/g.
- STO impaired feed conversion efficiency but did not affect spleen or pancreas size.
- Decreased serum enzymes (LDH, AST) and proteins (albumin) were observed at higher doses, along with bursa of Fabricius regression.
Conclusions:
- Scirpentriol toxicosis in chickens presents a distinct pattern compared to T-2 toxin and DAS.
- STO exhibits significant toxicity in broiler chickens, warranting further investigation.
- Specific dose-dependent effects on growth, organ weights, and serum biochemistry highlight STO's toxic potential.