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Published on: January 17, 2018

Diagnosis by sheer coincidence

Wojciech Wróbel1, Maciej Sosnowski, Krystian Wita

  • 1Medical University of Silesia, Katowice, Poland. wowr@wp.pl

The International Journal of Cardiovascular Imaging
|July 2, 2009
PubMed

Insights

This case report details an elderly patient with corrected transposition of the great arteries (CTGA) and subvalvular pulmonary stenosis, diagnosed using multislice computed tomography (MSCT). MSCT proved valuable for diagnosing these rare cardiac conditions in an older adult.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Oncology

Background:

  • Fludarabine chemotherapy for Hodgkin's lymphoma can have cardiac side effects.
  • Corrected transposition of the great arteries (CTGA) is a complex congenital heart defect.
  • Subvalvular pulmonary stenosis is a narrowing of the heart valve.

Observation:

  • A 69-year-old woman presented with palpitations and worsening heart failure post-fludarabine treatment.
  • Echocardiography showed findings consistent with CTGA.
  • Multislice computed tomography (MSCT) confirmed CTGA and identified subvalvular pulmonary stenosis.

Findings:

  • This is one of the oldest reported cases of CTGA with subvalvular pulmonary stenosis.
  • MSCT provided detailed anatomical information for diagnosis.
  • The patient's symptoms were potentially exacerbated by fludarabine in the context of underlying complex congenital heart disease.

Implications:

  • MSCT is a valuable tool for diagnosing complex congenital heart disease, especially in older adults.
  • Early diagnosis and management of CTGA and associated conditions are crucial for patient outcomes.
  • Understanding potential drug-induced cardiac complications in patients with pre-existing heart conditions is important for oncologists and cardiologists.

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