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A Comprehensive Protocol for Manual Segmentation of the Medial Temporal Lobe Structures
Published on: July 2, 2014
Right anterior temporal lobe atrophy and person-based semantic defect: a detailed case study
Thomas Busigny1, Laurence Robaye, Laurence Dricot
1Université Catholique de Louvain (UCL), Faculté de Psychologie et des Sciences de l'Education (PSP), Unité de Cognition et Développement (CODE), Place du Cardinal Mercier, 10, B-1348 Louvain-la-Neuve, Belgium. thomas.busigny@uclouvain.be
Abstract:
We report a new case of a right temporal pole variant of frontotemporal dementia (Rtv-FTLD), MD, who presented a slowly progressive deterioration of the recognition of familiar and famous people. We thoroughly investigated MD's face processing and semantic abilities, including a neuroimaging investigation. This analysis revealed a cross-modal person-based deficit together with a more general semantic alteration. However, there was no evidence of impairment in face perception, including holistic processing, or of an abnormal pattern of brain activation in face-sensitive cortical areas. We discuss the nature of face processing in the Rtv-FTLD and the context of a person-based semantic defect.
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