Related Experiment Video
Updated: Jun 22, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
Published on: March 26, 2018
Transcatheter aortic valve replacement: a potential option for the nonsurgical patient
Jigar H Patel1, Sunil T Mathew, Thomas A Hennebry
1Department of Internal Medicine, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA.
Insights
Transcatheter aortic valve replacement (TAVR) offers a feasible and effective option for patients with severe aortic stenosis denied surgery. Ongoing research and technological advancements may position TAVR as a viable alternative to traditional surgical valve replacement.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Technology
Background:
- Rising incidence of aortic stenosis due to increased life expectancy.
- High operative mortality excludes many patients from surgical aortic valve replacement.
- Limited mortality benefit from current alternative treatments like medical therapy or valvuloplasty.
Purpose of the Study:
- To review current transcatheter aortic valve replacement (TAVR) technology.
- To present available outcome data for TAVR in high-risk patients.
- To discuss the potential of TAVR as an alternative to surgical aortic valve replacement.
Main Methods:
- Review of clinical trial data on transcatheter aortic valve replacement (TAVR).
- Analysis of preliminary outcome data for TAVR devices.
- Description of current TAVR technology and its application.
Main Results:
- Transcatheter aortic valve replacement (TAVR) is demonstrated as feasible and effective in improving symptoms for patients with severe aortic stenosis.
- Preliminary trial results indicate positive outcomes for TAVR in surgically denied patients.
- Technical challenges and operator learning curve are noted limitations.
Conclusions:
- Transcatheter aortic valve replacement (TAVR) shows promise for patients with severe aortic stenosis who are not candidates for surgery.
- Continued technological advancements and operator experience are expected to enhance TAVR's efficacy.
- TAVR may become a viable alternative to traditional surgical aortic valve replacement in the future.
Abstract:
With improved life expectancy, the incidence of aortic stenosis is rising. However, up to one-third of patients who require lifesaving surgical aortic valve replacement are denied surgery due to a high operative mortality rate. Such patients can only be treated with medical therapy or percutaneous aortic valvuloplasty, neither of which has been shown to improve mortality. With advances in interventional cardiology, transcatheter methods have been developed for aortic valve replacement. Clinical trials are investigating these devices in patients with severe aortic stenosis that have been denied surgery. Preliminary results from these trials suggest that transcatheter aortic valve replacement (TAVR) is not only feasible, but an effective way to improve symptoms. In this review, we describe the current technology and display available outcome data. Though technical challenges and operator learning curve limit optimal use of the current technology, continued experience and advancements in technology may one day make TAVR a viable alternative to traditional surgical aortic valve replacement.
Related Concept Videos
Mitral Stenosis III: Medical Management
Aortic Regurgitation III: Medical Management
Peripheral Artery Disease III: Interprofessional Care