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Updated: Jun 22, 2026

Scoring Central Nervous System Inflammation, Demyelination, and Axon Injury in Experimental Autoimmune Encephalomyelitis
Published on: February 23, 2024
[Smell: integrating neurodegeneration and autoimmunity - a personal view]
Samuel-Datum Moscavitch1, Martine Szyper-Kravitz, Yehuda Shoenfeld
1Center for Autoimmune Diseases and Department of Medicine B, Chaim Sheba Medical Center Tel- Hashomer, Tel Aviv University, Tel Aviv, 52621, Israel. moscavitch@yahoo.com.br
Abstract:
Throughout human evolution, smell lost its important role to be replaced by other senses. Although, it retained a "role"in several "healing" practices. The aim of this review was to analyze the possible roles and influences of olfaction on higher brain functions, like mood and memory, and in contrast heightened the influence of pathologies such as Alzheimer's disease and schizophrenia on the olfactory function, based on recent animal and human data. In this neuro-psychiatric approach, the immune system could have a central role.
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