Prevalence and severity of hypertensive retinopathy in children

Bethany J Foster1, Huma Ali, Silvia Mamber

  • 1Division of Nephrology, Department of Pediatrics, McGill University, Montral, Quebec, Canada. beth.foster@muhc.mcgill.ca

Clinical Pediatrics
|July 3, 2009
PubMed

Insights

Retinal exams in hypertensive children show low prevalence of retinopathy, with only mild abnormalities found. Current recommendations for routine retinal screening in this population may need reconsideration due to limited evidence of harm.

Area of Science:

  • Ophthalmology
  • Pediatric Nephrology
  • Public Health

Background:

  • The National High Blood Pressure Education Program (NHBPEP) recommends retinal examinations for hypertensive children to detect target organ damage.
  • Hypertensive retinopathy is a potential complication of high blood pressure in pediatric populations.

Purpose of the Study:

  • To determine the prevalence and severity of hypertensive retinopathy in children diagnosed with hypertension.
  • To evaluate the utility of routine retinal examinations in this demographic within a real-world clinical setting.

Main Methods:

  • Retrospective review of medical records of 83 children diagnosed with hypertension.
  • Analysis of ophthalmological examinations performed within 12 months of hypertension diagnosis in 35 children.
  • Direct ophthalmoscopy by pediatric ophthalmologists.

Main Results:

  • Only 3 out of 35 (8.6%) children examined had hypertensive retinopathy.
  • The retinopathy detected was generally mild.
  • Prevalence was low even in children selected for examination, likely representing a higher-risk group.

Conclusions:

  • The prevalence of hypertensive retinopathy in children is low.
  • Mild retinal abnormalities in hypertensive children lack strong evidence of adverse outcomes.
  • Reconsideration of NHBPEP recommendations for routine retinal examinations in hypertensive children is warranted.

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...